Weekly Puzzle - Found in Virginia

In 1840 Charleston, Kanawha, Virginia (now West Virginia) we find the household of Nicholas Trindle, which consists of one male 30-40, one female 20-30, and two children under five, one boy and one girl.   To date I have found no other records for Nicholas who would have been born between 1800 and 1810.

Listed a few lines later we find the household of Jno (Jonathon?) Trindle.  Here we find another boy and girl under age 5, a male 30-40 and a female 40-50.  

Who are these Trindles?  Is the 40-50 year old female perhaps the mother rather than wife of Jno? She might also be another relative or nurse come to take care of the children.

I find no evidence of a Trindle family in Virginia before or after 1840, although an individual does pop up here and there who was born in Virginia.  

Any clues are welcome